MedTech West lunchseminar with professor Anna -Carin Olin and Jörgen Östling from PExA
Although highly desired, there are currently no non-invasive methods to collect samples from distal airways for robust biomarker analysis.
Researchers from the Breath Analyses Research-group at the Sahlgrenska University Hospital have developed a simple non-invasive method to sample biological material from small airways.
By asking the patient to breath into the PExA instrument, small droplet particles that are formed from the lining fluid when small airways close and re-open, can be measured and collected. It has been shown that the molecular makeup of this sample matrix is similar to broncho-alveolar lavage fluid. Interesting data from small pilot studies show an aberrant molecular composition of PEx samples from subjects with, asthma, chronic obstructive lung-disease, gastro-esophageal reflux and also from transplanted patients with chronic rejection.
Because PEx sample originate from a site close to where the pathological processes take place, there are reasons to believe that PExA-based biomarkers have the potential to detect disease at an earlier stage and with higher specificity than what may be expected from blood-based biomarkers. In prospect the method carries potential to become a valuable tool in basic research as well as in clinical practice.
In this lunchseminar, Anna-Carin Olin and Jörgen Östling will describe the PExA method, current research and the future plan for the method and the PExA company.
When? 11:30-13:00 on 11 April, 2018
Where? Hjärtats aula, Vita stråket 12, Sahlgrenska University Hospital
Participants registered before 12:00 on 9 April will be served a light lunch.
VERY WELCOME TO AN INTERESTING LUNCHSEMINAR!
The MedTech West Team